Basically you should pick the fights you can win. There's no reason to stay in early game fight e.g. 2 Sturm pios vs 1 conscript. In that case it's better to insta retreat. If you lose 4 models it's just waste of manpower and most likely your health has also gone down which would require medics.
Of course this is a situation depended. In later stages there might be situation where you can bait huge blob into your trap / opponent who is microing somewhere else, you can get a nice nade into the middle of the squad. And this way perhaps even squad wipe.
But in my opinion you should take less chances (atleast in early game) and retreat instead of stay in a fight you can't win.
But please strategists give more detailed tips how you pick your fights.
